Description

Falch et al proposed a staging classification for patients with anorectal malignant melanoma (ARMM). This can be helpful in determining prognosis and for management planning. The authors are from multiple universities in Europe, the United States and Israel.


 

Patient selection: anorectal malignant melanoma (excluding cutaneous melanoma of perianal skin)

 

Most anorectal melanomas occur on or near the pectinate line.

 

Staging is performed based on:

(1) clinical assessment

(2) histology

(3) PET scan

(4) transrectal ultrasound (TRUS)

(5) pelvic MRI

(6) sentinel lymph node mapping (using the double-tracer technique)

(7) examination of organs for distant metastases (especially bone, liver and lung)

 

Parameters:

(1) invasion of muscularis propria

(2) regional spread

(3) lymph node metastases

(4) distant metastases

Muscularis Propria

Regional Spread

Lymph Node Metastases

Distant

Stage

negative

absent

negative

negative

I

invasion

absent

negative

negative

II

invasion

present

NA

negative

III

invasion

NA

positive

negative

III

NA

NA

NA

NA

IV

 

In theory there should be an in situ stage if there is no invasion.

 

Stage

Management (Figure 1)

I

abdomino-perineal resection

II

wide local excision with adjuvant radiation therapy OR palliative abdomino-perineal resection

III

wide local excision with adjuvant radiation therapy

IV

wide local excision with adjuvant radiation therapy OR palliative abdomino-perineal resection

 


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