Falch et al proposed a staging classification for patients with anorectal malignant melanoma (ARMM). This can be helpful in determining prognosis and for management planning. The authors are from multiple universities in Europe, the United States and Israel.
Patient selection: anorectal malignant melanoma (excluding cutaneous melanoma of perianal skin)
Most anorectal melanomas occur on or near the pectinate line.
Staging is performed based on:
(1) clinical assessment
(2) histology
(3) PET scan
(4) transrectal ultrasound (TRUS)
(5) pelvic MRI
(6) sentinel lymph node mapping (using the double-tracer technique)
(7) examination of organs for distant metastases (especially bone, liver and lung)
Parameters:
(1) invasion of muscularis propria
(2) regional spread
(3) lymph node metastases
(4) distant metastases
Muscularis Propria |
Regional Spread |
Lymph Node Metastases |
Distant |
Stage |
negative |
absent |
negative |
negative |
I |
invasion |
absent |
negative |
negative |
II |
invasion |
present |
NA |
negative |
III |
invasion |
NA |
positive |
negative |
III |
NA |
NA |
NA |
NA |
IV |
In theory there should be an in situ stage if there is no invasion.
Stage |
Management (Figure 1) |
I |
abdomino-perineal resection |
II |
wide local excision with adjuvant radiation therapy OR palliative abdomino-perineal resection |
III |
wide local excision with adjuvant radiation therapy |
IV |
wide local excision with adjuvant radiation therapy OR palliative abdomino-perineal resection |
Specialty: Hematology Oncology, Surgery, general, Dermatology