HLA Screening to Identify Asian Patient at Risk for Carbamazepine-Associated Stevens-Johnson Syndrome

Purpose: To identify a patient who may be at increased risk for carbamazepine-associated Stevens Johnson Syndrome (SJS).

Info MyLikes MyPaths

Evaluation

Are you evaluating a patient prior to starting carbamazepine therapy?

Yes

Does the patient have an Asian ancestry?

Yes

Does the patient have HLA-B*1502?

Does the patient have HLA-B*0702?

Results

Please fill out required fields.

Results Interpretation and Description References Next Steps

Data complete?

Evaluation appropriate?

Is the patient at increased risk for the Stevens Johnson Syndrome after starting carbamazepine therapy?

The risk of a severe hypersensitivity reaction to carbamazepine therapy

Caution: A qualified health practitioner should verify all results.
Keep patient data confidential and comply with all legal requirements.

Please visit our website Medicalalgorithms.com for Description and Interpretation and further algorithms you may want to consider in the next steps of your evaluation. All information should be verified by a qualified health professional, and all use is subject to Medicalalgorithms.com Terms and Conditions. © Copyright Medicalalgorithms.com Limited

Interpretation and Description

References

Next Steps in Evaluation

Diagnosis

Risk Factors
Laboratory Tests
- Determining Isoniazid Acetylation Phenotype Based on Measurement of Urinary Isoniazid and Acetylisoniazid
- ABCB1 Polymorphism Test Prior to Therapy with Docetaxel or Irinotecan
Other Testing
- Methotrexate Toxicity & MTHFR (Methelenetetrahydrofolate Reductase) C677T Polymorphism
- Impact of CYP2C19 Phenotype on Clopidogrel Response
Criteria For Diagnosis
- Warfarin for Polymorphism in Cytochrome P450 (CYP) CYP2C9 | Medical Algorithm
Severity, Prognosis, Stage
- Predict Severe Toxicity Associated with Fluorouracil (5-FU) Therapy

Therapy

Selection
Pharmacogenetics
Dosage Adjustments
- Efavirenz Dose Reduction in HIV-1 Infected Patient Based on CYP2B6 Genotype

Monitoring

Response To Therapy
Adverse Effects
- Efavirenz Dose Reduction in HIV-1 Infected Patient Based on CYP2B6 Genotype
- Methotrexate Toxicity & MTHFR (Methelenetetrahydrofolate Reductase) C677T Polymorphism

Specialty

Toxicology
Emergency Medicine
Critical Care
Genetics

Objective

risk factors
selection
adverse effects

ICD-10

L51.1 - Bullous erythema multiforme

Info

Purpose: To identify a patient who may be at increased risk for carbamazepine-associated Stevens Johnson Syndrome (SJS).

Specialty: Toxicology, Emergency Medicine, Critical Care, Genetics

Objective: risk factors, selection, adverse effects

ICD-10: L51.1,

Save Data

Identifier

Enter 1 to 5 characters as ID

Email

Your registered email

Other

Email to

Please separate multiple email IDs with comma (,)

Consult Report

Identifier

Enter 1 to 5 characters as ID

Add to MyPath

Select path

New path