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Study of Musallam et al for Predicting Survival of a Patient with Non-Transfusion Dependent Beta Thalassemia

Description

Musallam et al used anemia and iron overload to determine the risk of mortality in a patient with non-transfusion-dependent beta-thalassemia. This can help to identify a patient who may require more aggressive management. The authors are from multiple institutions in the Middle East, Europe, and the United States.


Patient selection: non-transfusion dependent beta-thalassemia

Median age at last observation: 30.1 years

 

Parameters:

(1) hemoglobin in g/dL (as measure of anemia)

(2) serum ferritin in ng/mL (as measure of iron overload)

 

Hemoglobin

Serum Ferritin

Survival Probability at 70 Years

> 10 g/dL

<= 800 ng/mL

99%

<= 10 g/dL

<= 800 ng/mL

91%

> 10 g/dL

> 800 ng/mL

91%

<= 10 g/dL

> 800 ng/mL

76%

 


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