Criteria for a cliical diagnosis of dengue - all of the following:
(1) residence or travel to an area endemic for dengue
(2) fever (temperature >= 38°C or history of fever lasting 2-7 days)
(3) 2 or more additional clinical findings (see below)
(4) exclusion of other diagnoses that explain the findings better
where:
• Illness during a dengue outbreak might be more flexible.
Additional clinical findings:
(1) nausea and/or vomiting
(2) rash
(3) aches and pains
(4) tourniquet test positive
(5) leukepenia
(6) any warning sign (see below)
Warning signs:
(1) abdominal pain or tenderness
(2) persistent vomiting
(3) clinical fluid accumulation
(4) mucosal bleeding
(5) lethargy or restlessness
(6) hepatomegaly > 2 cm
(7) increase in hematocrit (hemoconcentration) AND sudden decrease in platelet count to < 100,000 per µL (thrombocytopenia)
Laboratory confirmation requires some form of evidence:
(1) positive RT-PCR reaction
(2) seroconversion
(3) IgM anti-dengue antibody
