Criteria for Hepatic Fibrosis in Patient with Chronic Viral Hepatitis C (HCV)

 

Parameters:

(1) serum AST in IU/L

(2) serum ALT in IU/L

(3) platelet count per µL

 

AST to ALT ratio =

= (AST) / (ALT)

Parameter	Finding	Points
AST to ALT ratio	< 1	0
	>= 1	1
platelet count	>= 150,000 per µL	0
	< 150,000 per µL	1

 

where:

• The AST to ALT ratio >= 1 is equivalent to AST >= ALT.

 

total score =

= SUM(points for bother parameters)

 

Interpretation:

• minimum score: 0

• maximum score: 2

• A patient with a score of 2 is at risk for significant hepatic fibrosis.