Taher et al reported the Thalassemia-Related Thrombosis Risk Scoring System (TRT-RSS) for predicting the risk of thrombosis in a patient with thalassemia. This can help to identify a patient who may benefit from interventions to reduce the risk of thrombosis. The authors are from the American University of Beirut, University of Milan and International Network of Hematology (London).
Patient selection: thalassemia
Parameter:
(1) age in years
(2) hemoglobin in g/dL
(3) serum ferritin concentration in micrograms per L
(4) transfusion status
(5) history of splenectomy
Parameter
Finding
Points
age in years
<= 35 years
0
> 35 years
2.5
hemoglobin
>= 9 g/dL
0
< 9 g/dL
2.5
serum ferritin
< 1,000 µg/L
0
>= 1,000 µg/L
2.0
transfusion status
regularly transfused
0
not regularly transfused
3.5
splenectomized
no
0
yes
6.5
where:
• Not regularly transfused is less than 1 transfusion per 6 weeks over past 26 weeks (6 months).
total score =
= SUM(points for all 5 parameters)
Interpretation:
• minimum score: 0
• maximum score: 17
• The higher the score the greater the risk of thrombosis.
Score
Risk
0 to 9
low
9.5 to 13.5
intermediate
14 to 17
high
To read more or access our algorithms and calculators, please log in or register.
