le Riche et al developed a simple activity index for systemic lupus erythematosus. The authors are from St. Joseph's Hospital in London, Ontario.
Measures:
(1) mucocutaneous count
(2) musculoskeletal count
(3) migraine indicator
(4) hemoglobin and albumin indicator
(5) urinalysis indicator
|
Mucocutaneous Feature |
Finding |
Indicator |
|---|---|---|
|
SLE rash |
absent |
0 |
|
|
present |
1 |
|
mucosal ulcers |
absent |
0 |
|
|
present |
1 |
|
Raynaud's phenomenon |
absent |
0 |
|
|
present |
1 |
mucocutaneous count =
= SUM(points for all 3 mucocutaneous features)
|
Musculoskeletal Feature |
Finding |
Indicator |
|---|---|---|
|
arthritis |
absent |
0 |
|
|
present |
1 |
|
arthralgia |
absent |
0 |
|
|
present |
1 |
|
myalgia |
absent |
0 |
|
|
present |
1 |
|
muscle weakness |
absent |
0 |
|
|
present |
1 |
musculoskeletal count =
= SUM(points for all 4 mucocutaneous features)
|
Feature |
Finding |
Indicator |
|---|---|---|
|
migraine |
absent |
0 |
|
|
present |
1 |
|
hemoglobin and albumin |
hemoglobin <= 13.6 g/dL |
1 |
|
|
serum albumin <= 3.7 g/dL |
1 |
|
|
BOTH hemoglobin > 13.6 g/dL, AND serum albumin > 3.7 g/dL |
0 |
|
urinalysis |
proteinuria (> 0.5 g/d, or > 3+) |
1 |
|
|
cellular casts |
1 |
|
|
>= 5 RBC per high power field |
1 |
|
|
none of the above findings |
0 |
where:
• Proteinuria and cellular casts are from the SLE 1982 criterion for renal disease.
T =
= (0.3 * (mucocutaneous count)) + (0.14 * (musculoskeletal count)) + (0.3 * (migraine indicator)) + (0.5 * (hemoglobin and albumin indicator)) + (0.3 * (urinalysis indicator))
index =
= EXP(T) - 1
Interpretation:
• minimum score: 0
• maximum score: 11.94
• The higher the score the greater the disease activity.
Purpose: To evaluate activity of systemic lupus erythematosus (SLE) in a patient using the index of le Riche et al.
Specialty: Immunology/Rheumatology
Objective: disease progression
ICD-10: M32,
