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The AGES Prognostic Score for Papillary Thyroid Carcinoma

Purpose: To evaluate a patient with papillary thyroid carcinoma using the AGES prognostic score.

Description

The AGES (age, grade, extent, size) prognostic score can be used to estimate prognosis for  patients with papillary carcinoma of the thyroid. This can help identify patients who may need more or less aggressive therapy. The authors are from the Mayo Clinic.


Parameters:

(1) A: age

(2) G: grade

(3) E: extent

(4) S:size

 

Parameter

Finding

Points

age

< 40 years

0

 

>= 40 years

0.05 * (age)

grade

grade 1

0

 

grade 2

1

 

grade 3

3

 

grade 4

3

extent

confined to thyroid

0

 

extrathyroid

1

 

distant spread

3

tumor size

maximum diameter in cm

0.2 * (diameter in cm)

 

where:

• I could not find where the grading of the tumor was defined.

 

AGES score =

= SUM(points for all 4 parameters)

 

Interpretation:

• minimum score: < 0.1

• maximum score: > 12

• The higher the score, the worse the prognosis.

 

AGES Score

Risk Group

25 Year Mortality Rate (1987)

< 4.00

1 (minimal)

2%

4.00 – 4.99

2

24%

5.00 – 5.99

3

49%

>= 6.00

4 (high)

93%

 


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Specialty

Objective

ICD-10