Data:
(1) average weight of prepared blank in grams
(2) density of suppository blank
(3) number of suppositories to be prepared
(4) density of drug
(5) dose of drug per suppository in grams
density ratio of drug to base =
= (density drug) / (density of base)
amount of drug required for the number of suppositories to be prepared =
= (number of suppositories) * (grams drug per suppository)
amount of suppository base displaced by drug =
= (amount of total drug required) / (density ratio)
amount of base required for suppositories in grams =
= ((number of suppositories) * (average weight of prepared base)) – (amount of suppository base displaced by drug)
