The staging system of Cierny and Mader for osteomyelitis uses both the anatomy of the bone infection and the physiologic status of the host. This allows development of precise treatment guidelines to match the conditions of the infection. This system does not designate acute versus chronic infection, since large areas of necrotic tissue need to be removed regardless of duration of the infection.
Anatomic Type |
Description |
Stage 1 |
medullary osteomyelitis |
Stage 2 |
superficial osteomyelitis |
Stage 3 |
localized osteomyelitis |
Stage 4 |
diffuse osteomyelitis |
Medullary osteomyelitis (Stage 1):
(1) infection confined to the intramedullary space
(2) examples: hematogenous osteomyelitis, infected intramedullary rod
Superficial osteomyelitis (Stage 2):
(1) focus of osteomyelitis in bone contiguous to a focus of soft tissue infection or ulceration
Localized osteomyelitis (Stage 3):
(1) full-thickness cortical sequestration that can be removed surgically without compromise of bony stability
Diffuse osteomyelitis (Stage 4):
(1) through-and-through process requiring an intercallary resection of bone to arrest the disease process
(2) includes infections with loss of bony stability before or after surgical debridement
Physiologic Class |
Subtype |
Description |
A host |
|
normal host |
B host |
Bs |
systemic compromise |
|
Bl |
localized compromise |
|
Bls |
systemic and local compromise |
C host |
|
treatment worse than the disease |
Type of Compromise |
Subtype |
Factors |
systemic |
Bs |
malnutrition |
|
|
renal failure |
|
|
hepatic failure |
|
|
diabetes mellitus |
|
|
chronic hypoxia, including hemoglobinopathy |
|
|
immune disease |
|
|
malignancy |
|
|
extremes of age |
|
|
immunosuppression or immune deficiency |
local |
Bl |
chronic lymphedema |
|
|
venous stasis |
|
|
major vessel compromise |
|
|
arteritis |
|
|
extensive scarring |
|
|
radiation fibrosis |
|
|
small vessel disease |
|
|
neuropathy |
|
|
heavy tobacco use (>= 2 packs of cigarettes per day) |
Specialty: Infectious Diseases, Surgery, orthopedic