Description

Tilford et al identified factors associated with mortality for children with head injury. The authors are from the Universities of Arkansas and California at San Francisco.


Patient selection: pediatric patients admitted to pediatric intensive care units after head injury.

 

Parameters:

(1) low bicarbonate (<= 15 mmol/L)

(2) low potassium (<= 3 mmol/L)

(3) high glucose (> 200 mg/dL)

(4) fixed pupils

(5) Glasgow Coma Score <= 8 on admission

(6) vasoactive infusion

 

Parameter

Odds Ratio

95% CI

p value

low bicarbonate

4.5

1.4 – 14.48

0.012

low potassium

4.23

1.21 – 14.8

0.024

high glucose

3.6

1.22 – 10.63

0.020

fixed pupils

8.91

2.73 – 29.09

< 0.001

Glasgow Coma Score

4.65

1.39 – 15.59

0.013

vasoactive infusion

5.41

1.98 – 14.8

0.001

 

 

Parameter

Finding

Points

serum bicarbonate

<= 15 mmol/L

1.504

 

> 15 mmol/L

0

serum potassium

<= 3 mmol/L

1.442

 

> 3 mmol/L

0

serum glucose

> 200 mg/dL

1.281

 

<= 200 mg/dL

0

pupils

both fixed

2.188

 

not fixed

0

Glasgow Coma Scale

> 8 on admission

1.539

 

<= 8 on admission

0

vasoactive infusion

given

1.688

 

not given

0

 

X =

= SUM(points for parameters present) – 5.065

 

probability of mortality =

= EXP(X) / (1 + EXP(X) =

= 1 / (1 + EXP((-1) * X))

 

Infants <= 1 year of age were noted to have a significantly higher mortality rate than for children > 1 year of age.


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