TNM Classification and Staging of Pediatric Soft Tissue Sarcomas

Description

Previous to the Fifth Edition of the AJCC Staging Manual, pediatric soft tissue sarcomas were classified separately from the adult soft tissue sarcomas. This distinction is no longer shown in the Fifth Edition (see above).

Clinical Classification

Parameter	Finding	TNM
primary tumor	cannot be assessed	TX
	no evidence of primary tumor	T0
	tumor localized in the organ or tissue of origin	T1
	tumor involving one or more contiguous organs or tissues or with adjacent malignant effusion	T2
size	greatest dimension of tumor < 5 cm	T code "a"
	greatest dimension of tumor >= 5 cm	T code "b"
regional lymph nodes	regional lymph nodes cannot be assessed	NX
	no evidence of regional lymph node involvement	N0
	evidence of regional lymph node involvement	N1
metastasis	presence of distant metastasis cannot be assessed	MX
	no evidence of distant metastasis	M0
	evidence of distant metastasis	M1

Pathologic Classification

Parameter	Finding	TNM
primary tumor	cannot be assessed	pTX
	no evidence of primary tumor	pT0
	tumor localized in the organ or tissue of origin, excision complete and margins histologically free	pT1
	tumor invades beyond the organ or tissue of origin; excision complete and margins histologically free	pT2
	tumor invades beyond the organ or tissue of origin; excision incomplete	pT3
	pT3 + microscopic residual tumor	pT3a
	pT3 + macroscopic residual tumor, or adjacent malignant effusion	pT3b
	pT3 + surgical exploration with tumor not resected	pT3C
regional lymph nodes	regional lymph nodes cannot be assessed	pNX
	no evidence of regional lymph node involvement	pN0
	evidence of regional lymph node involvement	pN1
	pN1 + regional lymph node metastasis completely resected	pN1a
	pN1 + regional lymph node metastasis incompletely resected	pN1b
metastasis	presence of distant metastasis cannot be assessed	pMX
	no evidence of distant metastasis	pM0
	evidence of distant metastasis	pM1

Clinical Staging

Clinical Stage	cTNM
I	T1 N0 M0
II	T2 N0 M0
III	T1 N1 M0, T2 N1 M0
IV	T1 N0 M1, T2 N0 M1, T1 N1 M1, T2 N1, M1

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TNM Classification and Staging of Pediatric Soft Tissue Sarcomas

Description

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