Hepatocellular carcinoma can be classified and staged using the AJCC TNM scheme.
Number of Tumor Nodules |
Size of Largest Tumor Nodule |
Other |
T Code |
1 |
<= 2 cm |
without vascular invasion |
T1 |
1 |
<= 2 cm |
with vascular invasion |
T2 |
1 |
> 2 cm |
without vascular invasion |
T2 |
1 |
> 2 cm |
with vascular invasion |
T3 |
> 1 in one lobe |
<= 2 cm |
without vascular invasion |
T2 |
> 1 in one lobe |
<= 2 cm |
with vascular invasion |
T3 |
> 1 in one lobe |
> 2 cm |
without vascular invasion |
T3 |
> 1 in one lobe |
> 2 cm |
with vascular invasion |
T3 |
> 1 in more than 1 lobe |
|
|
T4 |
>= 1 |
|
involvement of major branch of portal or hepatic vein |
T4 |
>= 1 |
|
invasion of adjacent organs other than gallbladder |
T4 |
>= 1 |
|
perforation of visceral peritoneum |
T4 |
Site |
Finding |
Code |
regional lymph nodes |
no metastases present |
N0 |
|
metastases present |
N1 |
distant sites |
no metastases present |
M0 |
|
metastases present |
M1 |
TNM |
Stage |
T1 N0 M0 |
I |
T2 N0 M0 |
II |
T3 N0 M0 |
IIIA |
T1 – T3, N1, M0 |
IIIB |
T4, any N, M0 |
IVA |
any T, any N, M1 |
IVB |
Specialty: Hematology Oncology, Surgery, general, Gastroenterology
ICD-10: ,