Trypophobia refers to the triggering of a fear response upon seeing a cluster of small holes, dots, circles, or bumps.
Trypa is Greek for "hole"
Some triggers include:
(1) insect eyes
(2) coral
(3) honeycomb
(4) paint splatter
(5) polka dots
Some triggers may be drug-induced.
The condition is considered significant if:
(1) it triggers intense fear or anxiety
(2) it is disabling