The administration of some medications can result in diarrhea when they are administered through an enteral feeding tube.
Factors contributing to diarrhea:
(1) medication with high osmolarity
(2) presence of sorbitol, mannitol or other poorly absorbed osmotic agent
(3) gluten in a patient with celiac disease
(4) gastrointestinal motility agent
Differential diagnosis:
(1) infectious diarrhea
(2) other diarrheal disease
Management:
(1) A liquid medication that is hyperosmolar should be diluted (usually with sterile water) prior to administration.
(2) The amount of sorbitol or other osmotic agent should be determined and reduced to a tolerable level.
(3) Gluten-free medications may benefit a patient with celiac disease.
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Purpose: To identify medications administered by an enteral feeding tube which could be causing a patient to have diarrhea.
Specialty: Pharmacology, clinical, Nutrition
Objective: risk factors, adverse effects
ICD-10: R19.7,