Valerian root is prepared from Valeriana officinalis which is a perennial flowering plant.
Extracts contain alkaloids (actinidine, valerine, chatinine, others), acids (valeric, formic, malic), gamma-aminobutyric acid (GABA), tannin and resin.
The preparation has been used to treat anxiety, sedation, muscle relaxant and insomnia.
Adverse effects:
(1) headache
(2) drowsiness
(3) dry mouth
(4) gastrointestinal upset
(5) signs of liver damage
Sudden discontinuation after prolonged use may be associated with a withdrawal reaction.
(1) delirium
(2) cardiac arrhythmias
(3) vivid dreams
(4) excitability and/or insomnia
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Specialty: Pharmacology, clinical
ICD-10: ,
