Puhr et al reported the VAGAS score for predicting the outcome of a patient with gastroesophageal carcinoma. Some parameters are based on alarm symptoms, some on endoscopic findings and one on pathologic exam. The authors are from Medical University of Vienna and Comprehensive Cancer Center in Vienna.
VAGAS is based on Viennese, Advanced Gastroesopheal and Alarm Symptoms.
Patient selection: advanced or metastatic gastro-esophageal cancer
Parameters:
(1) weight loss
(2) dyspepsia
(3) stenosis on endoscopy
(4) ulcer or active bleeding
(5) HER2 status
Parameter
Finding
Points
weight loss
no
0
yes
1
dyspepsia
no
0
yes
-1
stenosis
no
0
yes
1
ulcer or bleeding
no
0
yes
-1
HER2 status
no
0
yes
-1
total score =
= SUM(points for all 5 parameters)
Interpretation:
• minimum score: -3
• maximum score: 2
• A negative is associated with a better survival for a grim condition.
Total Score
1 Year Survival
2-Year Survival
-3
60%
30%
-2
60%
30%
-1
58%
30%
0
31%
8%
1
39%
7%
2
20%
3%
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