Zygomycosis can rarely affect neonates or infants. These can be serious infections that must treated aggressively.
Clinical involvement may include:
(1) cutaneous
(2) gastrointestinal
(3) disseminated
(4) rhinocerebral
(5) pulmonary
Risk factors for infection:
(1) prematurity (if neonate)
(2) neutropenia
(3) immunosuppression
(4) diabetes mellitus, especially with ketoacidosis
Poor prognostic findings:
(1) disseminated disease AND age < 1 year
(2) failure to treat aggressively with surgery and amphotericin B or other appropriate antifungal agent
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Specialty: Infectious Diseases, Pedatrics