Description

Zygomycosis can rarely affect neonates or infants. These can be serious infections that must treated aggressively.


Clinical involvement may include:

(1) cutaneous

(2) gastrointestinal

(3) disseminated

(4) rhinocerebral

(5) pulmonary

 

Risk factors for infection:

(1) prematurity (if neonate)

(2) neutropenia

(3) immunosuppression

(4) diabetes mellitus, especially with ketoacidosis

 

Poor prognostic findings:

(1) disseminated disease AND age < 1 year

(2) failure to treat aggressively with surgery and amphotericin B or other appropriate antifungal agent


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